Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

Abstract Background Over the past decade genome-wide association studies (GWAS) have been applied to aid in the understanding of the biology of traits. The success of this approach is governed by the underlying effect sizes carried by the true risk variants and the corresponding statistical power to...

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Bibliographic Details
Main Author: The Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Molecular Autism
Subjects:
Autism spectrum disorder
Genome-wide association study
Meta-analysis
Genetic correlation
Heritability
Gene-set analysis
Online Access:http://link.springer.com/article/10.1186/s13229-017-0137-9

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http://link.springer.com/article/10.1186/s13229-017-0137-9

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