Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Abstract The liposoluble tanshinones are bioactive components in Salvia miltiorrhiza and are widely investigated as anti-cancer agents, while the molecular mechanism is to be clarified. In the present study, we identified that the human fragile histidine triad (FHIT) protein is a direct binding prot...

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Bibliographic Details
Main Authors: Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu, Xisong Ke
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91708-z