A Novel Integrated Way for Deciphering the Glycan Code for the FimH Lectin
The fimbrial lectin FimH from uro- and enteropathogenic <i>Escherichia coli</i> binds with nanomolar affinity to oligomannose glycans exposing Manα1,3Man dimannosides at their non-reducing end, but only with micromolar affinities to Manα1,2Man dimannosides. These two di...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/23/11/2794 |