Rs7903146 variant of TCF7L2 gene and rs18012824 variant of PPARG2 gene (Pro12Ala) are associated with type 2 diabetes mellitus in Novosibirsk population

Rs7903146 variant of TCF7L2 gene and rs18012824 variant of PPARG2 gene (Pro12Ala) are associated with type 2 diabetes mellitus in Novosibirsk population

Aim.  To investigate the association of polymorphisms in TCF7L2 and PPARG2 genes with type 2 diabetes mellitus (T2DM) in Novosibirsk population. Materials and Methods. We examined 391 patients with T2DM and 556 individuals with normal glucose metabolism. Allelic identification was performed wit...

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Bibliographic Details
Main Authors: Irina Arkad'evna Bondar', Maksim Leonidovich Filipenko, Olesya Yur'evna Shabel'nikova, Ekaterina Alexandrovna Sokolova
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-12-01
Series:Сахарный диабет
Subjects:
type 2 diabetes mellitus
genetics
beta-cell dysfunction
insulin resistance
pparg2
tcf7l2
Online Access:https://dia-endojournals.ru/dia/article/viewFile/3846/4138

Internet

https://dia-endojournals.ru/dia/article/viewFile/3846/4138

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