An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis

Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear. In this study, we show that the mitotic shutdown is due to an unmet requirement for act...

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Bibliographic Details
Main Authors: Satdip Kaur, Andrew B Fielding, Gisela Gassner, Nicholas J Carter, Stephen J Royle
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00829