Differential Impact of TGFB1 Variation by Metastatic Status in Androgen-Deprivation Therapy for Prostate Cancer

Differential Impact of TGFB1 Variation by Metastatic Status in Androgen-Deprivation Therapy for Prostate Cancer

Transforming growth factor-β1 (TGF-β1) plays a dual role in cancer, acting as a tumor suppressor in the early stage of cancer development and as a tumor promoter in the later stage of cancer progression in various cancers. In this study, we investigated the association between genetic polymorphisms...

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Bibliographic Details
Main Authors: Masaki Shiota, Naohiro Fujimoto, Takashi Matsumoto, Shigehiro Tsukahara, Shohei Nagakawa, Shohei Ueda, Miho Ushijima, Eiji Kashiwagi, Ario Takeuchi, Junichi Inokuchi, Takeshi Uchiumi, Masatoshi Eto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
androgen-deprivation therapy
metastasis
prostate cancer
SNP
TGFB1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.697955/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.697955/full

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