Computed tomographic assessment of lung aeration at different positive end-expiratory pressures in a porcine model of intra-abdominal hypertension and lung injury

Abstract Background Intra-abdominal hypertension (IAH) is common in critically ill patients and is associated with increased morbidity and mortality. High positive end-expiratory pressures (PEEP) can reverse lung volume and oxygenation decline caused by IAH, but its impact on alveolar overdistension...

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Bibliographic Details
Main Authors: Adrian Regli, Siavash Ahmadi-Noorbakhsh, Gabrielle Christine Musk, David Joseph Reese, Peter Herrmann, Martin Joseph Firth, J. Jane Pillow
Format: Article
Language:English
Published: SpringerOpen 2021-10-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:https://doi.org/10.1186/s40635-021-00416-5