A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2.

Frizzled 8-associated Antiproliferative Factor (APF) is a sialoglycopeptide urinary biomarker of interstitial cystitis/painful bladder syndrome (IC/PBS), a chronic condition of unknown etiology with variable symptoms that generally include pelvic and/or perineal pain, urinary frequency, and urgency....

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Bibliographic Details
Main Authors: Jayoung Kim, Susan K Keay, Sungyong You, Massimo Loda, Michael R Freeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3516501?pdf=render