Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety

Abstract Tetrahydrocurcumin (THC) is a major metabolite of curcumin and plays an important role in curcumin-induced biological effects. THC is a promising preventive and chemotherapeutic agent for cancer. A series of new pyrazole derivatives of THC have been synthesized as potent anticancer agents....

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Bibliographic Details
Main Authors: Ahmed Mahal, Ping Wu, Zi-Hua Jiang, Xiaoyi Wei
Format: Article
Language:English
Published: SpringerOpen 2017-11-01
Series:Natural Products and Bioprospecting
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13659-017-0143-9