Tenascin-C induces prolonged constriction of cerebral arteries in rats

Tenascin-C induces prolonged constriction of cerebral arteries in rats

Tenascin-C (TNC), a matricellular protein, is induced in association with cerebral vasospasm after subarachnoid hemorrhage. The aim of this study was to assess the vasoconstrictive effects of TNC and its mechanisms of action on cerebral arteries in vivo. Two dosages (1 and 10 μg) of TNC were adminis...

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Bibliographic Details
Main Authors: Masashi Fujimoto, Hidenori Suzuki, Masato Shiba, Naoshi Shimojo, Kyoko Imanaka-Yoshida, Toshimichi Yoshida, Kenji Kanamaru, Satoshi Matsushima, Waro Taki
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Neurobiology of Disease
Subjects:
Tenascin-C
Cerebral vasospasm
Mitogen-activated protein kinase
Toll-like receptor 4
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113000314

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http://www.sciencedirect.com/science/article/pii/S0969996113000314

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