<i>CDK12</i>: A Potent Target and Biomarker for Human Cancer Therapy

<i>CDK12</i>: A Potent Target and Biomarker for Human Cancer Therapy

Cyclin-dependent kinases (CDKs) are a group of serine/threonine protein kinases and play crucial roles in various cellular processes by regulating cell cycle and gene transcription. Cyclin-dependent kinase 12 (<i>CDK12</i>) is an important transcription-associated CDK. It shows versatile...

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Bibliographic Details
Main Authors: Shujing Liang, Lifang Hu, Zixiang Wu, Zhihao Chen, Shuyu Liu, Xia Xu, Airong Qian
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
cyclin-dependent kinase 12
gene transcription
cell cycle
cell proliferation
DNA damage response
cancer therapy
Online Access:https://www.mdpi.com/2073-4409/9/6/1483

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https://www.mdpi.com/2073-4409/9/6/1483

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