Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy

Under physiological conditions, retinal pigment epithelium (RPE) is a cellular monolayer composed of mitotically quiescent cells. Tight junctions and adherens junctions maintain the polarity of RPE cells, and are required for cellular functions. In proliferative vitreoretinopathy (PVR), upon retinal...

Full description

Bibliographic Details
Main Authors: Hui Zou, Chenli Shan, Linlin Ma, Jia Liu, Ning Yang, Jinsong Zhao
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10136.pdf