MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice.

Three waves of H2AX phosphorylation (γH2AX) have been observed in male meiotic prophase I: the first is ATM-dependent and occurs at leptonema, while the second and third are ATR-dependent, occuring at zygonema and pachynema, respectively. The third wave of H2AX phosphorylation marks and silences uns...

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Bibliographic Details
Main Authors: Hanwei Jiang, Qian Gao, Wei Zheng, Shi Yin, Liu Wang, Liangwen Zhong, Asim Ali, Teka Khan, Qiaomei Hao, Hui Fang, Xiaoling Sun, Peng Xu, Tej K Pandita, Xiaohua Jiang, Qinghua Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6019819?pdf=render