MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice.
Three waves of H2AX phosphorylation (γH2AX) have been observed in male meiotic prophase I: the first is ATM-dependent and occurs at leptonema, while the second and third are ATR-dependent, occuring at zygonema and pachynema, respectively. The third wave of H2AX phosphorylation marks and silences uns...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-05-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6019819?pdf=render |