Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study

Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study

Background: The virological and immunological effects of the immunomodulatory drugs used for COVID-19 remain unknown. We evaluated the impact of interleukin (IL)-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and the antibody response in patients with COVID-19. Methods: Prospective cohort...

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Bibliographic Details
Main Authors: Mar Masiá, Marta Fernández-González, Sergio Padilla, Piedad Ortega, José A. García, Vanesa Agulló, Javier García-Abellán, Guillermo Telenti, Lucía Guillén, Félix Gutiérrez
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:EBioMedicine
Subjects:
Tocilizumab
SARS-CoV-2
COVID-19
Viral kinetics
Antibody responses
Anti-cytokine therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420303753

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http://www.sciencedirect.com/science/article/pii/S2352396420303753

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