Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes.

Inflammation is a highly complex biological response evoked by many stimuli. A persistent challenge in modeling this dynamic process has been the (nonlinear) nature of the response that precludes the single-variable assumption. Systems-based approaches offer a promising possibility for understanding...

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Bibliographic Details
Main Authors: Xu Dong, Panagiota T Foteinou, Steven E Calvano, Stephen F Lowry, Ioannis P Androulakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2823776?pdf=render