A novel Rho-like protein TbRHP is involved in spindle formation and mitosis in trypanosomes.

In animals and fungi Rho subfamily small GTPases are involved in signal transduction, cytoskeletal function and cellular proliferation. These organisms typically possess multiple Rho paralogues and numerous downstream effectors, consistent with the highly complex contributions of Rho proteins to cel...

Full description

Bibliographic Details
Main Authors: Kanwal Abbasi, Kelly N DuBois, Ka Fai Leung, Joel B Dacks, Mark C Field
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3214021?pdf=render