Engineering CD4+ T Cells to Enhance Cancer Immunity

This review presents key advances in combining T cell receptor (TCR) gene transfer to redirect T-cell specificity with gene engineering in order to enhance cancer-protective immune function. We discuss how emerging insights might be applied to CD4+ T cells. Although much attention has been paid to t...

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Bibliographic Details
Main Authors: Francesca Sillito, Angelika Holler, Hans J. Stauss
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/7/1721