High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation

High-throughput genetic screens in animals could benefit from an easy way to mark positive hits. Here the authors introduce photo-highlighting using a photoconvertible fluorescent protein, and in combination with stimulated Raman scattering (SRS) microscopy, define a role for BMP signaling in lipid...

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Bibliographic Details
Main Authors: Yong Yu, Ayse Sena Mutlu, Harrison Liu, Meng C. Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00944-3