Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels
<p>Abstract</p> <p>Background</p> <p>TRPM8 is a non-selective cation channel that belongs to the melastatin subfamily of the transient receptor potential (TRP) ion channels. TRPM8 is activated by voltage, cold and cooling compounds such as menthol. Despite its essential...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2009-11-01
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| Series: | Molecular Pain |
| Online Access: | http://www.molecularpain.com/content/5/1/62 |