The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples

The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples

Abstract Background It is frequently assumed that pre-invasive lesions are simpler precursors of cancer and will contain a limited subset of the genomic changes seen in their associated invasive disease. Driver mutations are thought to occur early, but it is not known how many of these are present i...

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Bibliographic Details
Main Authors: Henry M. Wood, Catherine Daly, Rebecca Chalkley, Burcu Senguven, Lisa Ross, Philip Egan, Preetha Chengot, Jennifer Graham, Neeraj Sethi, Thian K. Ong, Kenneth MacLennan, Pamela Rabbitts, Caroline Conway
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Genome Medicine
Subjects:
Pre-cancer
Oral cancer
Tumour progression
Online Access:http://link.springer.com/article/10.1186/s13073-017-0442-0

Internet

http://link.springer.com/article/10.1186/s13073-017-0442-0

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