Nano-Encapsulation of Mithramycin in Transfersomes and Polymeric Micelles for the Treatment of Sarcomas

Nano-Encapsulation of Mithramycin in Transfersomes and Polymeric Micelles for the Treatment of Sarcomas

Sarcomas are aggressive tumors which often show a poor response to current treatments. As a promising therapeutic alternative, we focused on mithramycin (MTM), a natural antibiotic with a promising anti-tumor activity but also a relevant systemic toxicity. Therefore, the encapsulation of MTM in nano...

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Bibliographic Details
Main Authors: Óscar Estupiñán, Claudia Rendueles, Paula Suárez, Verónica Rey, Dzohara Murillo, Francisco Morís, Gemma Gutiérrez, María del Carmen Blanco-López, María Matos, René Rodríguez
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
mithramycin
sarcoma
liposarcoma
chondrosarcoma
encapsulation
transfersomes
Online Access:https://www.mdpi.com/2077-0383/10/7/1358

Internet

https://www.mdpi.com/2077-0383/10/7/1358

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