A role for NKG2D in NK cell-mediated resistance to poxvirus disease.

Ectromelia virus (ECTV) is an orthopoxvirus (OPV) that causes mousepox, the murine equivalent of human smallpox. C57BL/6 (B6) mice are naturally resistant to mousepox due to the concerted action of innate and adaptive immune responses. Previous studies have shown that natural killer (NK) cells are a...

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Bibliographic Details
Main Authors: Min Fang, Lewis L Lanier, Luis J Sigal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2233669?pdf=render