In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics

In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics

Mydriasis is required prior to many eye examinations and ophthalmic surgeries. Nowadays, phenylephrine hydrochloride (PHE) and tropicamide (TPC) are extensively used to induce mydriasis. Several pharmaceutic dosage forms of these two active ingredients have been described. However, no optimal therap...

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Bibliographic Details
Main Authors: Pierre-Louis Destruel, Ni Zeng, Françoise Brignole-Baudouin, Sophie Douat, Johanne Seguin, Elodie Olivier, Melody Dutot, Patrice Rat, Sophie Dufaÿ, Amélie Dufaÿ-Wojcicki, Marc Maury, Nathalie Mignet, Vincent Boudy
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
mydriasis
drug release
in situ gelling
ophthalmic
delivery system
gellan gum
Online Access:https://www.mdpi.com/1999-4923/12/4/360

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https://www.mdpi.com/1999-4923/12/4/360

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