TLR2-Deficiency Promotes Prenatal LPS Exposure-Induced Offspring Hyperlipidemia

TLR2-Deficiency Promotes Prenatal LPS Exposure-Induced Offspring Hyperlipidemia

Toll-like receptor 2 (TLR2), which recognizes several lipopeptides and transduces inflammatory signaling, promotes the pathogenesis of diet-induced dyslipidemia and obesity. TLR2-deficient mice were shown to have improved insulin sensitivity and reduced diet-induced metabolic syndrome. Previous stud...

Full description

Bibliographic Details
Main Authors: Dayan Cao, Wenjia Wang, Shuhui Li, Wenjing Lai, Xiaoyong Huang, Jianzhi Zhou, Xin Chen, Xiaohui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
hyperlipidemia
prenatal lipopolysaccharide stimulation
TLR2
TLR4
VLDLR
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01102/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01102/full

Similar Items