TLR2-Deficiency Promotes Prenatal LPS Exposure-Induced Offspring Hyperlipidemia
Toll-like receptor 2 (TLR2), which recognizes several lipopeptides and transduces inflammatory signaling, promotes the pathogenesis of diet-induced dyslipidemia and obesity. TLR2-deficient mice were shown to have improved insulin sensitivity and reduced diet-induced metabolic syndrome. Previous stud...
Main Authors: | Dayan Cao, Wenjia Wang, Shuhui Li, Wenjing Lai, Xiaoyong Huang, Jianzhi Zhou, Xin Chen, Xiaohui Li |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-08-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2019.01102/full |
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