Repression of long non-coding RNA MEG3 restores nerve growth and alleviates neurological impairment after cerebral ischemia-reperfusion injury in a rat model

Repression of long non-coding RNA MEG3 restores nerve growth and alleviates neurological impairment after cerebral ischemia-reperfusion injury in a rat model

Objective: This study was performed to investigate effect of long non-coding RNA (lncRNA) MEG3 on nerve growth and neurological impairment in a rat model after cerebral ischemia-reperfusion injury (IRI) through the Wnt/β-catenin signaling pathway. Methods: Rat models of middle cerebral artery occlus...

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Bibliographic Details
Main Authors: Dong You, Hong You
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MEG3
Wnt/β-catenin signaling pathway
Cerebral ischemia-reperfusion injury
Neurological impairment
Neuronal apoptosis
Neuronal necrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218345670

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http://www.sciencedirect.com/science/article/pii/S0753332218345670

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