Metabolic and Immunological Shifts during Mid-to-Late Gestation Influence Maternal Blood Methylation of CPT1A and SREBF1

Metabolic and Immunological Shifts during Mid-to-Late Gestation Influence Maternal Blood Methylation of CPT1A and SREBF1

Mid-to-late gestation is a unique period in which women experience dynamic changes in lipid metabolism. Although the recent intensive epigenome-wide association studies (EWAS) using peripheral leukocytes have revealed that lipid-related traits alter DNA methylation, the influence of pregnancy-induce...

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Bibliographic Details
Main Authors: Shilpa Pavethynath, Chihiro Imai, Xin Jin, Naomi Hichiwa, Hidemi Takimoto, Motoko Okamitsu, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Ayako Fudono, Masaaki Muramatsu, Naoyuki Miyasaka, Noriko Sato
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
pregnancy
DNA methylation
CPT1A
SREBF1
leukocyte composition
Online Access:http://www.mdpi.com/1422-0067/20/5/1066

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http://www.mdpi.com/1422-0067/20/5/1066

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