Trouble shooting during bioanalytical estimation of drug and metabolites using LC-MS/MS: A review

Trouble shooting during bioanalytical estimation of drug and metabolites using LC-MS/MS: A review

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Bioanalysis frequently involves the measurement of very low analyte concentrations in complex and potentially variable matrices. An initial attempt has been made to apply a risk management tool to the bioanalytical method development like selection of spiked plasma volume, selection of internal stan...

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Bibliographic Details
Main Authors: Ganesh N Sharma, Man Mohan Singhal, K K Sharma, Jyotsana Sanadya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Bioanalysis
LC-MS/MS
Ion suppression
Matrix effect
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=1;spage=1;epage=10;aulast=Sharma

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http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=1;spage=1;epage=10;aulast=Sharma

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