<it>In vivo </it>monitoring of fetoplacental Vegfr2 gene activity in a murine pregnancy model using a Vegfr2-luc reporter gene and bioluminescent imaging

<p>Abstract</p> <p>Background</p> <p>Vascular endothelial growth factor receptor-2 (VEGFR2) plays a pivotal role in angiogenesis by eliciting vascular endothelial cell growth when bound to VEGF, a powerful pro-angiogenic ligand. While Vegf and Vegfr2 are expressed throu...

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Bibliographic Details
Main Authors: Rude Brian J, Bowers Susan D, Dunaway Chad W, Greene Jonathan M, Feugang Jean M, Ryan Peter L
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/9/1/51