Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis

Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis

Objective: We aimed to identify modularized structural atrophy of brain regions with a high degree of connectivity and its longitudinal changes associated with the progression of Alzheimer's disease (AD) using weighted gene co-expression network analysis (WGCNA), which is an unsupervised hierar...

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Bibliographic Details
Main Authors: Kenichiro Sato, Tatsuo Mano, Hiroshi Matsuda, Michio Senda, Ryoko Ihara, Kazushi Suzuki, Hiroyuki Arai, Kenji Ishii, Kengo Ito, Takeshi Ikeuchi, Ryozo Kuwano, Tatsushi Toda, Takeshi Iwatsubo, Atsushi Iwata
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219303079

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http://www.sciencedirect.com/science/article/pii/S2213158219303079

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