Identification by TCGA database search of five genes that are aberrantly expressed and involved in hepatocellular carcinoma potentially via DNA methylation changes

Abstract Background Various treatments for hepatocellular carcinoma (HCC) are utilized in clinical practice; however, the prognosis is still poor on account of high recurrence rates. DNA methylation levels of CpG islands around promoters (promoter CpGis) inversely regulate gene expression and closel...

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Bibliographic Details
Main Authors: Junya Matsushita, Takehiro Suzuki, Kazuyuki Okamura, Gaku Ichihara, Keiko Nohara
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Environmental Health and Preventive Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12199-020-00871-8