Copper interferes with selenoprotein synthesis and activity

Selenium and copper are essential trace elements for humans, needed for the biosynthesis of enzymes contributing to redox homeostasis and redox-dependent signaling pathways. Selenium is incorporated as selenocysteine into the active site of redox-relevant selenoproteins including glutathione peroxid...

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Bibliographic Details
Main Authors: Maria Schwarz, Kristina Lossow, Katja Schirl, Julian Hackler, Kostja Renko, Johannes Florian Kopp, Tanja Schwerdtle, Lutz Schomburg, Anna Patricia Kipp
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309514