Human Adipose Tissue-Derived Mesenchymal Stromal Cells Inhibit CD4+ T Cell Proliferation and Induce Regulatory T Cells as Well as CD127 Expression on CD4+CD25+ T Cells

Human Adipose Tissue-Derived Mesenchymal Stromal Cells Inhibit CD4+ T Cell Proliferation and Induce Regulatory T Cells as Well as CD127 Expression on CD4+CD25+ T Cells

Mesenchymal stromal cells (MSC) exert their immunomodulatory potential on several cell types of the immune system, affecting and influencing the immune response. MSC efficiently inhibit T cell proliferation, reduce the secretion of pro-inflammatory cytokines, limit the differentiation of pro-inflamm...

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Bibliographic Details
Main Authors: Agnese Fiori, Stefanie Uhlig, Harald Klüter, Karen Bieback
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
mesenchymal stromal cells
CD4 T cells
immunomodulation
regulatory T cells
CD127
Online Access:https://www.mdpi.com/2073-4409/10/1/58

Internet

https://www.mdpi.com/2073-4409/10/1/58

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