Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice

<p>Abstract</p> <p>Scurfy mice display the most severe form of multi-organ inflammation due to total lack of the CD4<sup>+</sup>Foxp3<sup>+ </sup>regulatory T cells (Treg) resulted from a mutation of the X-linked transcription factor Foxp3. A large repertoir...

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Bibliographic Details
Main Authors: Ju Shyr-Te, Fu Shu Man, Sung Sun-sang, Sharma Rahul
Format: Article
Language:English
Published: BMC 2009-02-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/20