Detection of Histoplasma DNA from Tissue Blocks by a Specific and a Broad-Range Real-Time PCR: Tools to Elucidate the Epidemiology of Histoplasmosis

Detection of Histoplasma DNA from Tissue Blocks by a Specific and a Broad-Range Real-Time PCR: Tools to Elucidate the Epidemiology of Histoplasmosis

Lack of sensitive diagnostic tests impairs the understanding of the epidemiology of histoplasmosis, a disease whose burden is estimated to be largely underrated. Broad-range PCRs have been applied to identify fungal agents from pathology blocks, but sensitivity is variable. In this study, we compare...

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Bibliographic Details
Main Authors: Dunja Wilmes, Ilka McCormick-Smith, Charlotte Lempp, Ursula Mayer, Arik Bernard Schulze, Dirk Theegarten, Sylvia Hartmann, Volker Rickerts
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Fungi
Subjects:
<i>Histoplasma</i> qPCR
broad-range qPCR
formalin-fixed paraffin-embedded (FFPE) samples
histoplasmosis
Online Access:https://www.mdpi.com/2309-608X/6/4/319

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https://www.mdpi.com/2309-608X/6/4/319

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