The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells

Background 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical, adversely affecting reproductive processes. The well-characterized canonical mechanism of TCDD action involves the activation of aryl hydrocarbon receptor (AhR) pathway, but AhR-independent mechanisms were also sugge...

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Bibliographic Details
Main Authors: Monika Ruszkowska, Agnieszka Sadowska, Anna Nynca, Karina Orlowska, Sylwia Swigonska, Tomasz Molcan, Lukasz Paukszto, Jan P. Jastrzebski, Renata E. Ciereszko
Format: Article
Language:English
Published: PeerJ Inc. 2020-01-01
Series:PeerJ
Subjects:
NGS
Porcine granulosa cells
TCDD
Transcriptome
AhR knock-down
Online Access:https://peerj.com/articles/8371.pdf

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https://peerj.com/articles/8371.pdf

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