The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells
Background 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical, adversely affecting reproductive processes. The well-characterized canonical mechanism of TCDD action involves the activation of aryl hydrocarbon receptor (AhR) pathway, but AhR-independent mechanisms were also sugge...
Main Authors: | Monika Ruszkowska, Agnieszka Sadowska, Anna Nynca, Karina Orlowska, Sylwia Swigonska, Tomasz Molcan, Lukasz Paukszto, Jan P. Jastrzebski, Renata E. Ciereszko |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-01-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/8371.pdf |
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