Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells

Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells

The ability of small extracellular vesicles (sEVs) to reprogram cancer cells is well established. However, the specific sEV components able to mediate aberrant effects in cancer cells have not been characterized. Integrins are major players in mediating sEV functions. We have previously reported tha...

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Bibliographic Details
Main Authors: Fabio Quaglia, Shiv Ram Krishn, George G. Daaboul, Srawasti Sarker, Raffaella Pippa, Josep Domingo-Domenech, Gaurav Kumar, Paolo Fortina, Peter McCue, William K. Kelly, Himisha Beltran, Qin Liu, Lucia R. Languino
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
prostate cancer
tumour growth
synaptophysin
aurora kinase a
iodixanol density gradient
Online Access:http://dx.doi.org/10.1080/20013078.2020.1761072

Internet

http://dx.doi.org/10.1080/20013078.2020.1761072

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