BMP9 inhibits proliferation and metastasis of HER2-positive SK-BR-3 breast cancer cells through ERK1/2 and PI3K/AKT pathways.

BMP9 inhibits proliferation and metastasis of HER2-positive SK-BR-3 breast cancer cells through ERK1/2 and PI3K/AKT pathways.

Bone morphogenetic protein 9 (BMP9), a member of TGF-β superfamily, is reported to inhibit the growth and migration of prostate cancer, osteosarcoma and triple-negative MDA-MB-231 breast cancer cells. However, little is known about the effect of on the biological behaviors of HER2-positive SK-BR-3 b...

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Bibliographic Details
Main Authors: Wei Ren, Yuehong Liu, Shaoheng Wan, Chang Fei, Wei Wang, Yingying Chen, Zhihui Zhang, Ting Wang, Jinshu Wang, Lan Zhou, Yaguang Weng, Tongchuan He, Yan Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4013047?pdf=render

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http://europepmc.org/articles/PMC4013047?pdf=render

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