Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES

Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES

The use of synthetic chromosomes and the recombinase-based SCRaMbLE system could enable rapid strain evolution through massive chromosome rearrangements. Here the authors present ReSCuES, which uses auxotrophic markers to rapidly identify yeast with rearrangements for strain engineering.

Bibliographic Details
Main Authors: Zhouqing Luo, Lihui Wang, Yun Wang, Weimin Zhang, Yakun Guo, Yue Shen, Linghuo Jiang, Qingyu Wu, Chong Zhang, Yizhi Cai, Junbiao Dai
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00806-y

Internet

https://doi.org/10.1038/s41467-017-00806-y

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