Rosiglitazone and myocardial infarction in patients previously prescribed metformin.

OBJECTIVE:Rosiglitazone was found associated with approximately a 43% increase in risk of acute myocardial infarction (AMI) in a two meta-analyses of clinical trials. Our objective is to estimate the magnitude of the association in real-world patients previously treated with metformin. RESEARCH DESI...

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Bibliographic Details
Main Authors: Colin R Dormuth, Malcolm Maclure, Greg Carney, Sebastian Schneeweiss, Ken Bassett, James M Wright
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2698985?pdf=render