Guidance on aneugenicity assessment

Guidance on aneugenicity assessment

Abstract The EFSA Scientific Committee was asked to provide guidance on the most appropriate in vivo tests to follow up on positive in vitro results for aneugenicity, and on the approach to risk assessment for substances that are aneugenic but not clastogenic nor causing gene mutations. The Scientif...

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Bibliographic Details
Main Authors: EFSA Scientific Committee (SC), Simon John More, Vasileios Bampidis, Claude Bragard, Thorhallur Ingi Halldorsson, Antonio F Hernández‐Jerez, Susanne Hougaard Bennekou, Kostas Koutsoumanis, Claude Lambré, Kyriaki Machera, Hanspeter Naegeli, Søren Saxmose Nielsen, Josef Schlatter, Dieter Schrenk, Dominique Turck, Maged Younes, Gabriele Aquilina, Margherita Bignami, Claudia Bolognesi, Riccardo Crebelli, Rainer Gürtler, Francesca Marcon, Elsa Nielsen, Christiane Vleminckx, Maria Carfì, Carla Martino, Daniela Maurici, Juan Parra Morte, Annamaria Rossi, Diane Benford
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:EFSA Journal
Subjects:
aneugenicity
micronucleus test
genotoxicity in vivo and in vitro
Online Access:https://doi.org/10.2903/j.efsa.2021.6770

Internet

https://doi.org/10.2903/j.efsa.2021.6770

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