Dose‐dependent Effect of Statin Therapy on Circulating CXCL12 Levels in Patients with Hyperlipidemia

Abstract Background HMG‐CoA reductase inhibitors (statins) have pleiotropic effects that are independent of cholesterol‐lowering, including a dose‐dependent effect on angiogenesis. Angiogenesis plays a critical role both in vascularization of the chronically ischemic myocardium and in stabilization...

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Bibliographic Details
Main Authors: Will Camnitz, Marie D Burdick, Robert M Strieter, Borna Mehrad, Ellen C Keeley
Format: Article
Language:English
Published: Wiley 2012-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/2001-1326-1-23