Role of Inflammasomes in Kidney Diseases via Both Canonical and Non-canonical Pathways

Inflammasomes, multiprotein complex induced by harmful factors in the body, play a crucial role in innate immunity. Activation of inflammasomes lead to the activation of casepase-1 and then the secretion of inflammatory cytokines, including IL-1β and IL-18, subsequently leading to a type of cell dea...

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Bibliographic Details
Main Authors: Huiling Xiang, Feng Zhu, Zhifeng Xu, Jing Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00106/full