The Elusive Link Between Cancer FDG Uptake and Glycolytic Flux Explains the Preserved Diagnostic Accuracy of PET/CT in Diabetes

The Elusive Link Between Cancer FDG Uptake and Glycolytic Flux Explains the Preserved Diagnostic Accuracy of PET/CT in Diabetes

This study aims to verify in experimental models of hyperglycemia induced by streptozotocin (STZ-DM) to what degree the high competition between unlabeled glucose and metformin (MET) treatment might affect the accuracy of cancer FDG imaging. The study included 36 “control” and 36 “STZ-DM” Balb/c mic...

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Bibliographic Details
Main Authors: Vanessa Cossu, Matteo Bauckneht, Silvia Bruno, Anna Maria Orengo, Laura Emionite, Enrica Balza, Patrizia Castellani, Patrizia Piccioli, Alberto Miceli, Stefano Raffa, Anna Borra, Maria Isabella Donegani, Sebastiano Carlone, Silvia Morbelli, Silvia Ravera, Gianmario Sambuceti, Cecilia Marini
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320300140

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http://www.sciencedirect.com/science/article/pii/S1936523320300140

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