The TSC Complex Is Required for the Benefits of Dietary Protein Restriction on Stress Resistance In Vivo

Protein restriction (PR) is important for the benefits of dietary restriction on longevity and stress resistance, but relevant nutrient sensors and downstream effectors in mammals remain poorly defined. We used PR-mediated protection from hepatic ischemia reperfusion injury to probe genetic requirem...

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Bibliographic Details
Main Authors: Eylul Harputlugil, Christopher Hine, Dorathy Vargas, Lauren Robertson, Brendan D. Manning, James R. Mitchell
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714005853