Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network

In higher eukaryotes, the endoplasmic reticulum (ER) contains a network of membrane tubules, which transitions into sheets during mitosis. Network formation involves curvature-stabilizing proteins, including the reticulons (Rtns), as well as the membrane-fusing GTPase atlastin (ATL) and the lunapark...

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Bibliographic Details
Main Authors: Songyu Wang, Hanna Tukachinsky, Fabian B Romano, Tom A Rapoport
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/18605