One-step automated bioprinting-based method for cumulus-oocyte complex microencapsulation for 3D in vitro maturation.

Three-dimensional in vitro maturation (3D IVM) is a promising approach to improve IVM efficiency as it could prevent cumulus-oocyte complex (COC) flattening and preserve its structural and functional integrity. Methods reported to date have low reproducibility and validation studies are limited. In...

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Bibliographic Details
Main Authors: Antonella Mastrorocco, Ludovica Cacopardo, Nicola Antonio Martino, Diana Fanelli, Francesco Camillo, Elena Ciani, Bernard A J Roelen, Arti Ahluwalia, Maria Elena Dell'Aquila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238812