Fatty Acid Synthase Contributes to Restimulation-Induced Cell Death of Human CD4 T Cells

Fatty Acid Synthase Contributes to Restimulation-Induced Cell Death of Human CD4 T Cells

Restimulation-induced cell death (RICD) is an apoptotic pathway triggered in activated effector T cells after T cell receptor (TCR) re-engagement. RICD operates at the peak of the immune response to ensure T cell expansion remains in check to maintain immune homeostasis. Understanding the biochemica...

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Bibliographic Details
Main Authors: Kelsey Voss, Christopher R. Luthers, Katherine Pohida, Andrew L. Snow
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
T cell
RICD
apoptosis
metabolism
fatty acid synthase
glycolysis
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00106/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2019.00106/full

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