Possible Involvement of p38 in Mechanisms Underlying Acceleration of Proliferation by 15-Deoxy-Δ12,14-prostaglandin J2 and the Precursors in Leukemia Cell Line THP-1

15-Deoxy-Δ12,14-prostaglandin J2 (15dPGJ2), which is a ligand for peroxisome proliferator-activated receptor γ (PPARγ), induced apoptosis of several human tumors including gastric, lung, colon, prostate, and breast. However, the role of PPARγ signals in other types of cancer cells (e.g., leukemia) e...

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Bibliographic Details
Main Authors: Yasutaka Azuma, Kyoko Watanabe, Masataka Date, Michiharu Daito, Kiyoshi Ohura
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324934